Paromomycin is an aminoglycoside antibiotic derived from the bacterium Micromonospora paromomycinica. It is primarily used to treat infections caused by certain parasites, particularly in cases of leishmaniasis and amebiasis. The chemical structure of paromomycin features multiple amino groups, which contribute to its mechanism of action by binding to the bacterial ribosome, inhibiting protein synthesis, and ultimately leading to cell death. Paromomycin is known for its relatively low toxicity compared to other aminoglycosides, making it a preferred option in specific therapeutic contexts. It is typically administered orally or parenterally, depending on the type of infection being treated. The substance is also characterized by its solubility in water, which facilitates its use in various formulations. However, like other aminoglycosides, it may have potential side effects, including nephrotoxicity and ototoxicity, necessitating careful monitoring during treatment. Overall, paromomycin serves as an important tool in the management of certain infectious diseases, particularly in regions where these conditions are endemic.

CAS 84420-34-8: Paromomycin (complex)

Paromomycin Sulfate

Ref: 3B-P2092