CAS 84499-64-9: L-Alanine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethylester

2-[(2-Amino-6-oxo-3H-purin-9-yl)methoxy]ethyl (2S)-2-aminopropanoate is a nucleotide analog, a synthetic compound designed to mimic the structure of natural nucleotides incorporated into DNA. It is derived from chemical synthesis to specifically interfere with viral DNA replication. The compound acts by selectively inhibiting viral DNA polymerase, an enzyme essential for the replication of viral genetic material. This inhibition effectively halts the proliferation of the virus, rendering it unable to reproduce within the host cell. The primary application of this compound is in antiviral therapies. It is used to manage and treat infections caused by DNA viruses, including herpesviruses. By integrating into the growing viral DNA chain, it causes premature chain termination and thus prevents the virus from multiplying. The compound's specificity for viral enzymes over host enzymes makes it a valuable tool in medical research and treatment, as it reduces potential cytotoxicity or side effects in human cells. This specificity underscores its importance in developing antiviral drugs, providing significant insights into viral pathogenesis and therapeutic mechanisms.

Acyclovir alanine is a pro-drug of Acyclovir. Acyclovir works by decreasing the production of DNA of the virus and it shows very low cytotoxicity.