
CAS 84573-16-0: (1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide
Formula:C29H31NO7
InChI:InChI=1S/C29H31NO7/c1-30(2)27(32)23-24(17-9-7-6-8-10-17)29(18-11-13-19(34-3)14-12-18)28(33,26(23)31)25-21(36-5)15-20(35-4)16-22(25)37-29/h6-16,23-24,26,31,33H,1-5H3/t23-,24-,26-,28+,29+/m1/s1
InChI key:InChIKey=DAPAQENNNINUPW-IDAMAFBJSA-N
SMILES:O[C@]12[C@]([C@@H]([C@@H](C(N(C)C)=O)[C@H]1O)C3=CC=CC=C3)(OC=4C2=C(OC)C=C(OC)C4)C5=CC=C(OC)C=C5
Synonyms:- Rocaglamide
- 1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, [1R-(1α,2α,3β,3aβ,8bβ)]-
- NSC 326408
- (1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide
- 1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, (1R,2R,3S,3aR,8bS)-
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Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Formula:C29H31NO7Purity:95.32% - 98.46%Color and Shape:SolidMolecular weight:505.56Rocaglamide
CAS:Rocaglamide is a synthetic compound that inhibits the mitochondrial membrane potential and induces apoptosis pathways. This compound also has potent antitumor activity in vivo, which may be due to its ability to inhibit the synthesis of DNA, RNA and protein in tumor cells. Rocaglamide inhibits cancer cells by inhibiting the production of ATP, which leads to cell death through necrosis or apoptosis. The hydroxyl group on rocaglamide's structure is thought to be responsible for its antitumor activity.Formula:C29H31NO7Purity:Min. 95%Molecular weight:505.56 g/molRocaglamide
CAS:Controlled ProductApplications Rocaglamide is derived from a Chinese medicinal plant Aglaia. Rocaglamide induces apoptosis in various human leukemia cell lines and in acute lymphoblastic leukemia, chronic myeloid leukemia and acute myeloid leukemia cells freshly isolated from patients. References Zhu, J., et. al.: Int. J. Cancer, 121, 1839 (2007)Formula:C29H31NO7Color and Shape:NeatMolecular weight:505.559