2'-Deoxy-5-fluorocytidine 5'-(dihydrogen phosphate), commonly referred to as a nucleotide analog, is a modified form of the nucleoside cytidine. This compound features a fluorine atom at the 5-position of the pyrimidine ring, which alters its biological activity and can inhibit DNA synthesis. The presence of the dihydrogen phosphate group indicates that it is a phosphorylated form, which is crucial for its role in biochemical pathways, particularly in nucleic acid metabolism. This substance is often studied for its potential applications in cancer therapy, as it can interfere with the replication of DNA in rapidly dividing cells. Its structural modifications enhance its stability and efficacy as an antimetabolite. Additionally, the compound is soluble in water, which facilitates its use in various biological assays and therapeutic formulations. Overall, 2'-deoxy-5-fluorocytidine 5'-(dihydrogen phosphate) exemplifies the intersection of chemistry and pharmacology, showcasing how structural changes can influence biological function.

2'-deoxy-5-fluorocytidine 5'-(dihydrogen phosphate)

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2'-Deoxy-5-fluorocytidine 5'-monophosphate is a nucleotide that is synthesized by the enzyme cytidine deaminase. It is used as a diagnostic agent in the detection of infectious diseases such as HIV, Mycobacterium tuberculosis, and cytomegalovirus (CMV). 2'-Deoxy-5-fluorocytidine 5'-monophosphate inhibits DNA synthesis by blocking the incorporation of deoxycytidylate into DNA. The compound is also an inhibitor of collagen synthesis in tissues and cells. Hydrogen bonds between this compound and its target enzymes are thought to be important for its inhibitory effects.

CAS 847-22-3: 2'-deoxy-5-fluorocytidine 5'-(dihydrogen phosphate)

2'-Deoxy-5-fluorocytidine 5'-monophosphate

Ref: 3D-FF86832

2'-Deoxy-5-Fluorocytidine 5'-Monophosphate

Ref: 4Z-C-4531