Benzamide, N-(3-acetylphenyl)-, also known by its CAS number 84833-25-0, is an organic compound characterized by the presence of a benzamide functional group attached to a 3-acetylphenyl moiety. This compound typically exhibits a white to off-white crystalline appearance and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. The structure features an amide linkage, which contributes to its potential as a building block in organic synthesis and pharmaceuticals. The presence of the acetyl group enhances its reactivity and may influence its biological activity, making it of interest in medicinal chemistry. Additionally, benzamide derivatives often display various properties such as antimicrobial, anti-inflammatory, or analgesic effects, depending on their specific structural modifications. As with many organic compounds, safety precautions should be observed when handling this substance, including the use of appropriate personal protective equipment to mitigate any potential health risks.

Benzamide, N-(3-acetylphenyl)-

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3-Acetylphenylbenzamide (APB) is a potent and selective HIV integrase inhibitor that inhibits the catalytic activity of HIV integrase. It has been shown to inhibit the replication of HIV-1 in human cells, including primary CD4+ T cells, by blocking the integration of viral DNA into the host genome. APB is structurally related to diketoacids, which are inhibitors of cellular protein synthesis, and can be used as a lead compound for developing therapeutics against HIV-1. The chemical structure of APB has been validated using nuclear magnetic resonance spectroscopy.

CAS 84833-25-0: Benzamide, N-(3-acetylphenyl)-

N-(3-Acetylphenyl)benzamide

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