CAS 851443-04-4: Rosuvastatin ethyl ester
Formula:C24H32FN3O6S
InChI:InChI=1/C24H32FN3O6S/c1-6-34-21(31)14-19(30)13-18(29)11-12-20-22(15(2)3)26-24(28(4)35(5,32)33)27-23(20)16-7-9-17(25)10-8-16/h7-12,15,18-19,29-30H,6,13-14H2,1-5H3/b12-11+/t18-,19-/m1/s1
Synonyms:- 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(N-methyl-N-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester
- Rosuvastatine
- ethyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate
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7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(N-methyl-N-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl es ter
CAS:Rosuvastatin is a statin drug that inhibits cholesterol synthesis by inhibiting the enzyme HMG-CoA reductase. Rosuvastatin has been shown to reduce high-sensitivity C-reactive protein (hsCRP) and low-density lipoprotein cholesterol (LDL-C), which are risk factors for cardiovascular disease, in patients with hypercholesterolemia. Rosuvastatin also has a high degree of potency and specificity for the HMG-CoA reductase enzyme and shows no significant cross-reactivity with other HMG-CoA reductase inhibitors. Rosuvastatin is metabolized by CYP3A4 and CYP2C9. Drugs that inhibit these enzymes may increase the plasma levels of rosuvastatin, while drugs that induce these enzymes may decrease the plasma levels of rosuvastatin.Formula:C24H32FN3O6SPurity:Min. 95%Color and Shape:PowderMolecular weight:509.59 g/molRosuvastatin Ethyl Ester
CAS:Applications Rosuvastatin ethyl ester (CAS# 851443-04-4) is an intermediate formed during the synthetic preparation of rosuvastatin, a pharmaceutical used to manage LDL cholesterol. References Sterk, D.; et al.: Tetrahedron Lett., 57, 1338 (2016); Olsson, A. G.; et al.: Am. Heart J., 144, 1044 (2002).Formula:C24H32FN3O6SColor and Shape:Off-White To Light BeigeMolecular weight:509.59Rosuvastatin Ethyl Ester (Ethyl (3R,5S,E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate)
CAS:Sulfonamides, nesoiFormula:C24H32FN3O6SColor and Shape:Off-White PowderMolecular weight:509.19959Rosuvastatine
CAS:Formula:C24H32FN3O6SPurity:99%Color and Shape:SolidMolecular weight:509.5907831999999Rosuvastatin Ethyl Ester
CAS:Formula:C24H32FN3O6SColor and Shape:White To Off-White SolidMolecular weight:509.59
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