Lorcaserin hydrochloride hemihydrate is a selective serotonin 2C receptor agonist primarily used as an anti-obesity medication. It is characterized by its ability to promote satiety and reduce appetite, making it effective in weight management. The compound appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration. Its molecular formula includes a hydrochloride salt form, contributing to its stability and bioavailability. Lorcaserin acts centrally in the brain, influencing neurotransmitter pathways associated with hunger and energy balance. The hemihydrate form indicates that it contains half a molecule of water for each molecule of the compound, which can affect its physical properties and stability. Due to its mechanism of action, lorcaserin has been studied for potential cardiovascular effects and safety profiles, leading to regulatory scrutiny. However, it was withdrawn from the market in 2020 due to concerns about an increased risk of cancer. Overall, lorcaserin hydrochloride hemihydrate exemplifies the complexities of pharmacological agents in weight management and their broader health implications.

Lorcaserin hydrochloride hemihydrate

856681-05-5: (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine hydrochloride hemihydrate, (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine Hydrochloride.1/2H2O

Lorcaserin is a serotonin 5-HT2C receptor agonist that is used to help with weight loss for obese patients. It is believed to be involved in the activation of 5-HT2C receptors in the anorexigenic pro-opiomelanocortin neurons. This results in decreased satiety and food intake.

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CAS 856681-05-5: Lorcaserin hydrochloride hemihydrate

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