2-Propynoic acid, 3-(2-pyridinyl)-, also known by its CAS number 858678-71-4, is an organic compound characterized by the presence of both a propyne and a pyridine moiety. This compound features a carboxylic acid functional group, which contributes to its acidic properties. The pyridine ring, a six-membered aromatic heterocycle containing one nitrogen atom, imparts unique electronic characteristics and can influence the compound's reactivity and solubility. Typically, compounds like this may exhibit moderate to high polarity due to the presence of the carboxylic acid group, making them soluble in polar solvents such as water and alcohols. Additionally, the presence of the pyridine ring can enhance the compound's ability to participate in hydrogen bonding and coordination with metal ions. The compound may also exhibit biological activity, making it of interest in medicinal chemistry and drug design. Overall, 2-Propynoic acid, 3-(2-pyridinyl)- is a versatile compound with potential applications in various chemical and pharmaceutical contexts.

2-Propynoic acid, 3-(2-pyridinyl)-

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Applications 3-(Pyridin-2-yl)propiolic Acid is a useful reagent in the regioselective Pd-catalyzed carbopalladation/decarboxylative allylic alkynylation of ortho-iodoallenamides.
References Hedouin, J., et al.: J. Org. Chem., 84, 10535 (2019)


3-(Pyridin-2-yl)propiolic Acid

_x005F_x000D_3-(2-Pyridyl)propiolic Acid

3-(2-Pyridyl)propiolic acid

3-Pyridylpropiolic acid is a pyridine-based chemical that is used as a building block in organic synthesis. It undergoes decarboxylative reactions with formaldehyde and boronic acids to produce the corresponding boronic ester or amide. 3-Pyridylpropiolic acid can be used in multicomponent reactions with other boronic acids, such as 2-(dimethylamino)pyrimidine-5-boronic acid, to produce aryl boronic acids. 3-Pyridylpropiolic acid has been shown to be an efficient starting material for the synthesis of biomolecules such as DNA, RNA, and proteins.

CAS 858678-71-4: 2-Propynoic acid, 3-(2-pyridinyl)-

3-(Pyridin-2-yl)propiolic Acid

Ref: TR-P841028

_x005F_x000D_3-(2-Pyridyl)propiolic Acid

Ref: IN-DA00IDSV

3-(2-Pyridyl)propiolic acid

Ref: 54-OR470616

3-(2-Pyridyl)propiolic acid

Ref: 3D-IJB67871