CAS: 858747-13-4

Drainh-A250 is a synthetic compound that is used to treat cancer. It has the ability to regulate the expression of genes in cancer cells, which may be due to its ability to inhibit adenoma growth and induce apoptosis in caco-2 cells. Drainh-A250 is also an electroneutral compound, meaning it does not have any net electrical charge. It is forskolin-sensitive and apically secreted, which means it is active in the human small intestine. This drug binds to the 3′ and 5′ regulatory region of DNA and inhibits the production of cyclic 3′,5′-phosphate monophosphate (cAMP), which regulates cell proliferation and differentiation.

DRAinh-A250 is a SLC26A3 inhibitor which blocks colonic fluid absorption and reduces constipation.