Benzothiazole, 6-ethynyl- is an organic compound characterized by the presence of a benzothiazole ring, which consists of a benzene fused to a thiazole moiety. This compound features an ethynyl group at the 6-position of the benzothiazole structure, contributing to its unique reactivity and properties. Benzothiazoles are known for their applications in various fields, including pharmaceuticals, agrochemicals, and materials science, due to their ability to act as fluorescent probes, dyes, or intermediates in chemical synthesis. The ethynyl group enhances the compound's potential for further functionalization, making it useful in synthetic organic chemistry. Additionally, compounds in this class often exhibit interesting electronic properties, which can be leveraged in the development of electronic materials or sensors. The specific characteristics, such as solubility, melting point, and reactivity, can vary based on the substituents and the overall molecular structure, but benzothiazole derivatives are generally recognized for their stability and versatility in chemical reactions.

Benzothiazole,6-ethynyl-

864376-04-5: Benzothiazole, 6-ethynyl- (9CI)

Benzothiazole, 6-ethynyl-

6-Ethynylbenzo[d]thiazole is an inhibitor of the kinase ALK5, which is a receptor for growth factor-β. This inhibition prevents the phosphorylation of the receptor and subsequent activation of downstream signaling pathways. 6-Ethynylbenzo[d]thiazole also inhibits other kinases such as TGF-β and activin. 6-Ethynylbenzo[d]thiazole has been shown to inhibit cellular proliferation in vitro by inhibiting the activity of enzymes that play a role in cell division. The compound has demonstrated inhibitory activity against a number of cell lines, including human cells and tumor cells derived from human cancer patients.

CAS 864376-04-5: Benzothiazole,6-ethynyl-

Benzothiazole, 6-ethynyl-

Ref: IN-DA00IE2G

6-Ethynylbenzo[d]thiazole

Ref: 3D-PJB37604

6-Ethynylbenzo[d]thiazole

Ref: 10-F243669