CAS: 869185-85-3

SB 203580 hydrochloride

SB-203580 Hydrochloride

SB 203580 hydrochloride is a p38 MAPK inhibitor that binds to the receptor site of the human serum albumin. It has been shown to have a significant effect on cell proliferation and cell migration in corneal endothelial cells and epidermal growth factor receptor-positive epithelial cells in culture. SB 203580 hydrochloride also inhibits protease activity, which may be related to its ability to inhibit tumor necrosis factor-α (TNF-α) production. SB 203580 hydrochloride is a nanoparticulate composition that can be used for treatment of inflammatory disorders such as asthma, COPD, and rheumatoid arthritis.

SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.