CAS 86953-81-3: 1-Piperidinecarboxylicacid, 2-hydroxy-, 1,1-dimethylethyl ester

tert-Butyl 2-hydroxypiperidine-1-carboxylate

tert-Butyl 2-hydroxypiperidine-1-carboxylate is a chiral compound that is used in the synthesis of glycolaldehyde and lactams. It can be synthesized by reacting a primary amine with an enol ether in the presence of acidic conditions, yielding an α-hydroxyketone. The tert-butyl 2-hydroxypiperidine carboxylate can then be recovered from the reaction mixture. This process is useful for organic chemistry because it yields both the α,β unsaturated ketone and the corresponding secondary alcohol. Glyceraldehyde is one example of such a product that can be made from this reaction.