CAS: 869748-10-7

A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.

A-770041 is a molecule that inhibits the kinase domain of thymidylate synthase (TS). It has shown efficacy in animal studies, and is currently being evaluated for use in clinical trials. A-770041 has been shown to inhibit the growth of myeloid leukemia cells by inhibiting TS. It also inhibits the proliferation of T cells and other types of cancer cells. A-770041 is orally active, and it may be able to treat cancer by inhibiting TS.