CAS 87392-05-0: (R)-tetrahydrofuran-2-carboxylic acid

(R)-(+)-2-Tetrahydrofuroic acid

Tetrahydro-2-furoic acid is an organic solvent with a dipole moment. Tetrahydro-2-furoic acid is a racemic mixture of the (R) and (S) stereoisomers, which can be separated by electrophoresis. The (R)-(+)-enantiomer has been shown to have higher activity than the (S)-(-)-enantiomer in many reactions, including the oxidation of benzyl alcohol to benzaldehyde. Tetrahydro-2-furoic acid is commercially available as a mixture of the two enantiomers or as pure (R)-(+)-tetrahydro-2-furoic acid. A kinetic study showed that the reaction time for this reaction was significantly lower when using pure tetrahydro-2-furoic acid than when using a mixture of the two optical isomers.

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