CAS: 876903-48-9

Stability Hygroscopic Applications 5-[2-Formyl-5-(hydroxymethyl)-1H-pyrrol-1-yl]-2-hydroxybenzoic Acid, is used for the synthesis of (-)-Funebrine, and (-)-Funebral, a unique pyrrole alkaloids isolated from flowers in Mexico, having therapeutic properties. References Tamura, O., et al.: J. Org. Chem., 69, 1475 (2004);

Salicylic acid is a natural compound found in many plants and has a variety of pharmacological effects. It is used as an anti-inflammatory, antipyretic (fever reducer), and analgesic (painkiller). Salicylic acid acts by inhibiting the activity of cyclooxygenase enzymes, which are responsible for the conversion of arachidonic acid to prostaglandins. The salicylic acid molecule can be synthesized from 2-hydroxybenzoic acid by hydroxymethylation. This reaction requires the addition of formaldehyde and results in the substitution of one OH group on 2-hydroxybenzoic acid with a methoxymethyl group. Sugar is often used as a reactant in this synthesis because it contains both OH groups that are required for the hydroxymethylation reaction. The lactose present in milk can also be used as a reactant because it contains both OH groups needed for the hyd