CAS 88-73-3: 1-Chloro-2-nitrobenzene

o-Nitrochlorobenzene is a chemical that belongs to the nitro group of compounds. It is used in the synthesis of various other chemicals, such as pharmaceuticals and dyes. o-Nitrochlorobenzene has been shown to be toxic to rats at higher doses, with evidence of toxicity including cavity formation and low energy levels. The long-term effects of o-nitrochlorobenzene are not well understood. There is also not enough information on its carcinogenicity in animals or humans.

1-Chloro-2-nitrobenzene was used in the synthesis of 1-hydroxybenzotriazole derivatives. It is important as a precursor to other compounds due to the two reactive sites present on the molecule. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Chloronitrobenzene

Applications 1-Chloro-2-nitrobenzene is a useful synthetic intermediate. It was used in the synthesis of 1-hydroxybenzotriazole derivatives. Reaction of 1-chloro-2-nitrobenzene with dinitrogen pentoxide in dichloromethane is strongly catalysed by H-Faujasite-720. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Fathalla, M., et al.: J. Chem. Soc. Pak., 33, 324 (2011); Claridge, R., et al.: J. Chem. Soc. Perkin Trans. II, 9, 1815, (1999)