Guanosine, 2'-deoxy-N,N-dimethyl- is a modified nucleoside that features a guanine base attached to a deoxyribose sugar, with two methyl groups substituted at the nitrogen atoms in the amino group of the guanine. This compound is part of the broader category of nucleosides, which are essential building blocks of nucleic acids like DNA and RNA. The presence of the dimethyl groups can influence the compound's solubility, stability, and interaction with biological systems. Typically, such modifications can enhance the pharmacological properties of nucleosides, making them of interest in medicinal chemistry and biochemistry. The CAS number 88127-22-4 uniquely identifies this substance, facilitating its recognition in scientific literature and databases. In terms of applications, modified nucleosides like this one are often explored for their potential roles in antiviral therapies, gene therapy, and as research tools in molecular biology. Overall, the structural modifications impart unique characteristics that can be leveraged for various biochemical applications.

Guanosine, 2'-deoxy-N,N-dimethyl-

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2’-Deoxy-N2-dimethylguanosine is a novel antiviral agent that inhibits the replication of human DNA viruses by binding to their diphosphate or monophosphate regions and inhibiting ribonucleotide reductase. It has also been shown to have anticancer properties in vitro.

2’-Deoxy-N2-dimethylguanosine

Nucleoside Derivatives -2-Modified purine nucleosides, N-Methylated nucleosides

CAS 88127-22-4: Guanosine, 2'-deoxy-N,N-dimethyl-

2’-Deoxy-N2-dimethylguanosine

Ref: 3D-AD163057

2'-Deoxy-N2,N2-dimethylguanosine

Ref: TM-TNU1168