![(1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacyclo…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F405851-1r-4ar-11r-12as-13s-16as-23r-24as-eicosahydro-5h-17h-123-1113-diethano-2h-14h-111-dioxacycloeicosino-23-b-1213-b-dipyridine.webp&w=3840&q=75)
CAS 88903-69-9: (1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b′]dipyridine
Formula:C28H50N2O2
InChI:InChI=1S/C28H50N2O2/c1-3-7-15-25-17-21-30-20-10-14-24(28(30)31-25)12-6-2-4-8-16-26-18-22-29-19-9-13-23(11-5-1)27(29)32-26/h23-28H,1-22H2/t23-,24+,25-,26-,27+,28+/m1/s1
InChI key:InChIKey=PQYOPBRFUUEHRC-HCKQMYSWSA-N
SMILES:[C@@]12([N@@]3CC[C@](O1)(CCCCCC[C@]4([C@@]5(O[C@](CCCCCC[C@]2(CCC3)[H])(CC[N@]5CCC4)[H])[H])[H])[H])[H]
Synonyms:- (-)-Araguspongin E
- (-)-Araguspongine E
- (-)-Xestospongin C
- (1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b′]dipyridine
- (1R,8R,10S,15S,22R,29S)-9,30-Dioxa-11,25-diazapentacyclo[20.6.2.2~8,11~.0~10,15~.0~25,29~]dotriacontane
- 5H,17H-1,23:11,13-Diethano-2H,14H-[1,11]dioxacycloeicosino[10,9-b:20,19-b']dipyridine, eicosahydro-, (4aR,11R,12aS,16aS,23R,24aS)-
- 5H,17H-1,23:11,13-Diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b′]dipyridine, eicosahydro-, (1R,4aR,11R,12aS,13S,16aS,23R,24aS)-
- 5H,17H-1,23:11,13-Diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b′]dipyridine, eicosahydro-, [1R-(1R*,4aR*,11R*,12aS*,13S*,16aS*,23R*,24aS*)]-
- Xestospongine C
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Found 5 products.
Xestospongin C
CAS:Xestospongin C ((-)-Xestospongin C) is an IP3R inhibitor and also a SERCA (sarco/endoplasmic reticulum Ca2+ ATPase) inhibitor.Formula:C28H50N2O2Purity:98%Color and Shape:Off-WhiteMolecular weight:446.71(-)-Xestospongin C
CAS:(-)-Xestospongin C is a surface-active molecule that has been shown to be membrane permeable. When applied to the surface of cells, it acts as a mimic for natural sphingolipids. (-)-Xestospongin C binds to the ryanodine receptor and blocks its activation by calcium ions, leading to inhibition of Ca2+ release from intracellular stores. It also inhibits the response of glycosidic bond-containing proteins in glycoprotein synthesis by inhibiting protein phosphorylation and subsequent dephosphorylation. (-)-Xestospongin C has been shown to have anti-inflammatory properties in models of inflammatory diseases such as ischemia reperfusion injury, which may be due to its ability to inhibit the production of proinflammatory cytokines such as IL-1β and TNFα.Formula:C28H50N2O2Purity:90%MinMolecular weight:446.71 g/mol
