CAS 90-02-8: Salicylaldehyde

Precursor to a variety of chelating agents.Salicylaldehyde is used as a precursor to prepare catechol, benzofuran, salicylaldehydimine and 3-carbethoxycoumarin. It is used for colorimetric assay of isoleucine as well as utilized for the determination of primary amine by fluorescence method. It is a key starting material to a various chelating agents. It is used as flavor and fragrance components. Its derivative salicylaldehyde thiosemicarbazone is used for the simultaneous determination of molybdenum and iron by spectrophotometric method. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Salicylaldehyde is a reactive compound that has been used as an antimicrobial and fluorescence probe. The protonation of salicylaldehyde is the rate-limiting step in its reaction with DNA, which leads to the formation of a chelate ligand. This binding results in intramolecular hydrogen bonding and linear calibration curves. Salicylaldehyde also reacts with coumarin derivatives to form a cyclic peptide, which can be used to measure glucose levels. The electrochemical impedance spectroscopy (EIS) of salicylic acid shows that it inhibits oxidative injury by preventing protein oxidation, lipid peroxidation, and hydroxyl radical production.