Cholinesterase refers to a group of enzymes that catalyze the hydrolysis of the neurotransmitter acetylcholine, playing a crucial role in the regulation of synaptic transmission in the nervous system. The most well-known forms are acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), which differ in their substrate specificity and tissue distribution. Cholinesterase is primarily found in the nervous system, but it is also present in other tissues, including the liver and plasma. The enzyme operates optimally at physiological pH and is sensitive to inhibition by certain chemicals, including organophosphates and carbamates, which can lead to toxic effects. In clinical settings, cholinesterase levels can be indicative of various health conditions, including exposure to neurotoxic agents or certain genetic disorders. The CAS number 9001-08-5 specifically refers to a form of cholinesterase that is often studied for its biochemical properties and potential therapeutic applications, including its role in drug metabolism and as a target for antidotes in poisoning scenarios.

Cholinesterase

9001-08-5: Acylcholine acylhydrolase, Acylcholine acylhydrolases, Benzoylcholinesterase, Benzoylcholinesterases, BtChoEase, Butyrylcholine esterase, Butyrylcholine esterases, Butyrylcholinesterase, Butyrylcholinesterases, Choline esterase, Choline esterase II, Choline esterases, Cholinesterase, Cholinesterase II, Cholinesterases, E.C. 3.1.1.8, E.C. 3.1.1.9, Ec 3.1.1.8, Esterasa, Colina, Esterase, Cholin-, Esterase, butyrylcholine, Propionylcholinesterase, Propionylcholinesterases, Protexia, Pseudocholinesterase, Pseudocholinesterases, Esterase, choline,  Cholinesterase, Equine Serum,  Butyrylcholinesterase from equine serum, butyrylcholine esterase F. horse serum

Butyrylcholinesterase is an enzyme made in the liver and found mainly in blood plasma. Butyrylcholinesterase (EC 3.1.1.8), also known as BChE or BuChE, is a nonspecific cholinesterase enzyme that hydrolyses choline-based esters. One unit of Butyrylcholinesterase will hydrolyze 1.0 μmole of butyrylcholine to choline and butyrate per minute at pH 8.0 and 37 °C.

CAS 9001-08-5: Cholinesterase

Butyrylcholinesterase human

Ref: 3D-FB179074