Creatine kinase (CK), with the CAS number 9001-15-4, is an enzyme that plays a crucial role in energy metabolism, particularly in muscle and brain tissues. It catalyzes the reversible transfer of a phosphate group from ATP (adenosine triphosphate) to creatine, forming phosphocreatine and ADP (adenosine diphosphate). This reaction is vital for maintaining energy homeostasis during periods of high energy demand, such as muscle contraction. Creatine kinase exists in several isoforms, primarily CK-MM (found in skeletal muscle), CK-MB (found in the heart), and CK-BB (found in the brain). The enzyme is typically present in the cytosol of cells and can also be found in mitochondria. Its activity can be measured in clinical settings to assess muscle damage or myocardial infarction, as elevated levels of CK in the bloodstream can indicate tissue injury. Creatine kinase is a dimeric enzyme, composed of two subunits, and its activity is influenced by factors such as pH, temperature, and the concentration of substrates and products.

Creatine kinase

9001-15-4: ATP:creatine N-phosphotransferase, ATP:creatine phosphotransferase, CK, Creatine Kinase, Creatine kinase (CK-BB iso-enzyme) (catalytic concentration), Creatine kinases, Creatine phosphokinase, Creatine phosphokinases, Creatine phosphotransferase, Creatine phosphotransferases, Creatinine phosphokinase, Creatinine phosphokinases, E.C. 2.7.3.2, Ec 2.7.3.2, Kinase (Phosphorylante), Creatine, Kinase (phosphorylating), creatine, Kinase (phosphorylierend), Kreatin-, Phosphocreatine kinase, Phosphocreatine kinases, Quinasa (Fosforilante), Creatina

Creatine kinase (also known phosphocreatine kinase or creatine phosphokinase, EC 2.7.3.2) in an enzyme that catalyzes the following reaction:creatine + ATP ⇌ phosphocreatine + ADPOne unit of creatine kinase will transfer 1.0 μmole of phosphate from phosphocreatine to ADP per min at pH 7.4 and 30 °C.

Creatine phosphokinase, type I, lyophilized powder, ≥150 units/mg protein

Creatine kinase (OcCK) converts creatine and ATP into phosphocreatine and ADP, crucial for ATP/ADP balance during high energy demand.

CAS 9001-15-4: Creatine kinase

Creatine phosphokinase, type I, lyophilized powder, ≥150 units/mg protein

Ref: 3D-JAA00115

Creatine kinase (OcCK)

Ref: TM-T76113

Creatine kinase (from Rabbit muscle)

Ref: 54-BIB3055