Glutaminase, with the CAS number 9001-47-2, is an enzyme that catalyzes the hydrolysis of glutamine to glutamate and ammonia. It plays a crucial role in nitrogen metabolism and is involved in various physiological processes, including neurotransmission and cellular metabolism. Glutaminase is found in various tissues, particularly in the brain and kidneys, and exists in multiple isoforms, each with distinct properties and regulatory mechanisms. The enzyme operates optimally at specific pH and temperature ranges, which can vary depending on its source. Glutaminase is also significant in the context of cancer metabolism, as many tumors exhibit increased glutamine consumption, making it a potential target for therapeutic intervention. Additionally, it is utilized in biotechnological applications, including the production of flavor enhancers and in the food industry. Its activity can be influenced by various factors, including substrate concentration, allosteric regulators, and post-translational modifications, making it a subject of interest in both basic and applied research.

Glutaminase

9001-47-2: <span class="text-smallcaps">L</span>-Glutaminase, <span class="text-smallcaps">L</span>-Glutamine deaminase, Amano 500, E.C. 3.5.1.2, Ec 3.5.1.2, Glutaminase, Glutaminase 1, Glutaminase C, Glutaminase C 100S, Glutaminase C 200, Glutaminase Daiwa C-100, Glutaminase Daiwa C100S, Glutaminase Daiwa SD-C 100S, Glutaminase FP, Glutaminase GT, Glutaminase Grade Ii From Escherichia*Coli, Glutaminase Grade Vii From Escherichia*Coli, Glutaminase I, Glutaminase SD C100S, Glutaminase from Bacillus subtilis, Glutaminases, Glutamine amidohydrolase, Glutamine aminohydrolase, Glutamine aminohydrolases, L-Glutaminase, L-Glutamine amidohydrolase, L-Glutamine deaminase, L-Glutamine deaminases, Sd C100S, Sumizyme GT, Y 600S, glutaminase grade V from escherichia*coli

Glutaminase (glutaminase I, L-glutaminase, glutamine aminohydrolase; EC 3.5.1.2) is an enzyme that catalyzes the following reaction:  L-glutamine + H2O → L-glutamate + NH4+  One unit of glutaminase will convert 1.0 μmole of L-glutamine into L-glutamate per min at pH 4.9 and 37 °C.

CAS 9001-47-2: Glutaminase

Glutaminase from escherichia coli

Ref: 3D-JAA00147

Glutaminase

Ref: 7W-GZ5356