CAS 9001-74-5: beta-lactamase F. enterobacter cloacae

Penase (Penicillinase) is an enzyme, which is a type of β-lactamase sourced from various bacterial strains capable of deactivating penicillin. It accomplishes this by targeting the β-lactam ring, a crucial structural component of penicillin antibiotics, and hydrolyzing it, thereby neutralizing the antibiotic effect. This enzymatic action is a defense mechanism employed by certain bacteria to survive in environments saturated with penicillin-based antibiotics. The primary application of Penase is in microbiological and biochemical research where understanding bacterial resistance mechanisms is critical. Scientists often utilize Penase to study resistance patterns in bacteria, evaluate enzyme kinetics, and develop strategies to counteract bacterial defense mechanisms. Additionally, it serves as an important tool in environmental microbiology, assisting researchers in exploring the dissemination of antibiotic resistance genes. The insights gained are invaluable in shaping the development of next-generation antibiotics that are effective against resistant bacterial strains, thus contributing to global healthcare initiatives against antibiotic resistance.

Penase is an enzyme, specifically a type of beta-lactamase, which is derived from bacterial sources. Its mode of action involves the hydrolysis of the beta-lactam ring present in penicillin molecules. This enzymatic activity renders penicillin inactive by breaking its critical structural component that is essential for its antibacterial activity. In research and clinical settings, Penase is utilized to study antibiotic resistance mechanisms and the effects of beta-lactamase production in bacteria. Additionally, it is used in laboratory assays to quantify penicillin or as a control to assess the specific activity of penicillin-targeted treatments. By understanding the interaction between penicillin and Penase, scientists can better comprehend the challenges posed by antibiotic-resistant strains and develop strategies to combat them. Its application is crucial in the field of microbiology, particularly in understanding the dynamics of bacterial adaptation and resistance.

beta lactamase I activity - min. 600.0 IU/mg

Penicillinase, a beta-lactamase, breaks down beta-lactam antibiotics, making them ineffective.

Beta-lactamase enzyme with sole specificity for penicillins. This product can be used in the sterility testing and microbial count determination in samples containing penicillins.

Beta-lactamase enzyme with sole specificity for penicillins. This product is available as a freeze-dried powder and can be used in the sterility testing and microbial count determination in samples containing penicillins.