Urate oxidase, also known as uricase, is an enzyme that catalyzes the oxidation of uric acid to allantoin, facilitating the breakdown of purines in the body. It is primarily found in certain microorganisms and some mammals, but humans lack this enzyme, which can lead to elevated levels of uric acid and conditions such as gout. The enzyme operates optimally at specific pH and temperature ranges, which can vary depending on the source organism. Urate oxidase is of significant interest in medical applications, particularly in the treatment of hyperuricemia and gout, as it can help lower uric acid levels in patients. The enzyme is typically produced through recombinant DNA technology for therapeutic use, ensuring a consistent and high-quality product. Additionally, urate oxidase has been studied for its potential in various biotechnological applications, including biosensors and bioremediation. Its CAS number, 9002-12-4, identifies it in chemical databases, facilitating research and regulatory processes.

Urate oxidase

9002-12-4: E.C. 1.7.3.3, Oxidasa, Urato, Oxidase, Urat, Oxydase, Urate, Urate oxidase, Urate:O2-oxidoreductase, Urate:O<sub>2</sub>-oxidoreductase, Uratoxidase, Uric acid oxidase, Uricase, Uricozyme, Oxidase, urate

r-Uricase (Thermostable) ex. Yeast, 3U/mg powder

Uricase

Uricase is very important for the determination of uric acid in biological fluids. Uricase is an important medical enzyme which can be used to determine urate in clinical analysis. The enzyme Urate oxidase (UO) catalyzes the oxidation of uric acid to 5-hydroxyisourate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Uricase, Candida utilis

Uricase catalyzes uric acid to allantoin in many mammals' peroxisomes, used in biochemistry.

Urate Oxidase, also known as uricase, catalizes the following reaction: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2.

CAS 9002-12-4: Urate oxidase

r-Uricase (Thermostable) ex. Yeast, 3U/mg powder

Ref: SR-95410

Uricase

Ref: 7W-GZ1482

Uricase, Candida utilis

Ref: 02-J60875

Urate oxidase

Ref: TM-T73617

Urate oxidase (from Yeast)

Ref: 3D-JAA00212

Urate oxidase (from Yeast)

Ref: 54-BIB3102