CAS 9004-02-8: Lipoprotein lipase

Lipoprotein lipase (LPL) is an enzyme, mainly involved in lipid metabolism, that hydrolyzes triglycerides.for obesity/diabetes-related cardiovascular diseases.

Lipoprotein lipase is a critical enzyme used to modulate lipid processing, primarily sourced from mammalian tissues. It functions by hydrolyzing triglycerides present in circulating chylomicrons and very low-density lipoproteins. This enzymatic process liberates free fatty acids, which can subsequently be utilized as energy by peripheral tissues or stored in adipose tissue. Lipoprotein lipase is pivotal in lipid metabolism, participating in maintaining homeostasis of plasma lipid levels. The enzyme is widely employed in biochemical and physiological research to explore mechanisms underlying lipid metabolism disorders, such as hyperlipidemia and atherosclerosis. Its role in metabolic pathways makes it invaluable for studies aiming to develop therapeutic strategies targeting lipid-related diseases. Additionally, lipoprotein lipase assays are utilized to measure enzymatic activity in various biological samples, facilitating the assessment of lipid metabolism in experimental settings. This enzyme, therefore, not only serves as a tool for scientific inquiry but also enhances our understanding of metabolic health and disease.