Freund's adjuvant, identified by the CAS number 9007-81-2, is a substance commonly used in immunology to enhance the immune response to antigens. It is composed of a mixture of mineral oil and emulsifying agents, which can include killed mycobacteria in the case of Freund's complete adjuvant. This formulation creates a depot effect, allowing for prolonged release of the antigen and stimulating a stronger immune response. Freund's adjuvant is characterized by its ability to promote both humoral and cellular immunity, making it valuable in vaccine development and research. However, its use is often limited to experimental settings due to potential side effects, such as local inflammation and granuloma formation. The adjuvant is typically administered via injection and is known for its effectiveness in eliciting robust immune responses in various animal models. Safety and ethical considerations are paramount when using Freund's adjuvant, particularly in the context of animal research and vaccine formulation.

Immunostimulants,adjuvants, Freund's

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Rhizoma dioscoreae is a traditional Chinese medicine that is used to treat cancer and inflammatory diseases. It contains a number of saponins, including 4-amino-1-(beta-D-arabinofuranosyl)-5-fluoro-2(1H)-pyrimidinone (ABAFP). ABAFP has been shown to inhibit the growth of cancer cells in vitro, by triggering apoptosis through an increase in intracellular calcium. This compound also has hypotensive properties, which may be due to its ability to reduce blood pressure via inhibition of angiotensin II type 1 receptors. ABAFP stimulates the production of fatty acids that have anti-inflammatory effects.

CAS 9007-81-2: Immunostimulants,adjuvants, Freund's

4-Amino-1-(β-D-arabinofuranosyl)-5-fluoro-2(1H)-pyrimidinone

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