Phytohemagglutinins (PHA) are a type of lectin derived primarily from the red kidney bean, Phaseolus vulgaris. They are characterized by their ability to agglutinate red blood cells and bind to specific carbohydrates, which makes them valuable in various biological and medical applications. PHA is a glycoprotein composed of multiple subunits, exhibiting a high molecular weight. It is known for its mitogenic properties, stimulating cell division in lymphocytes, which is useful in immunological studies. PHA is also utilized in laboratory settings for cell culture and as a tool in blood typing. In terms of safety, while PHA is generally considered safe in small amounts, it can be toxic if consumed in large quantities, as raw kidney beans contain higher concentrations of the lectin. Therefore, proper cooking is essential to deactivate the harmful effects. Overall, PHA serves as an important reagent in biochemistry and molecular biology, contributing to advancements in research and diagnostics.

Phytohemagglutinins

9008-97-3: Agglutinins and Lectins, phytohem-, Agglutinins and Lectins, phytohemagglutinins, Agglutinins and lectins, phytohemagglutinin, Agglutinins, phytohemagglutinin, Agglutinins, phytohemagglutinins, Hemagglutinins, phyto-, Hemagglutinins, phytohemagglutinins, Lectins, phytohemagglutinin, Lectins, phytohemagglutinins, PHA (phytohemagglutinins), Phytohem- agglutinins and Lectins, Phytohemagglutinin, Phytohemagglutinin-M, Phaseolus vulgaris, Phytohemagglutinins, Phytohemagglutinins agglutinins and Lectins, Phytolectin

Phytohemagglutinin is a plant-derived protein that belongs to the class of hemagglutinins. It is used in plant physiology and has been shown to stimulate lymphocyte transformation. This protein has also been shown to have biological properties, such as the ability to inhibit growth of kidney bean cells. Phytohemagglutinin can be used in immunological studies and may be useful for treating autoimmune diseases. In addition, this protein stimulates the production of IL-2 by T cells, which can lead to leukemia or lymphoma. The optimum concentration for phytohemagglutinin is 0.1% (w/v).

Phytohemagglutinin

PHA-M, a lectin from red kidney beans, induces apoptosis by upping Bax protein and activating caspase-3; has anti-tumor effects.

CAS 9008-97-3: Phytohemagglutinins

Phytohemagglutinin

Ref: 3D-JAA00897

Phytohemagglutinin

Ref: TM-T13818