Glutathione peroxidase (GPx) is an important antioxidant enzyme that plays a crucial role in protecting cells from oxidative damage. It catalyzes the reduction of hydrogen peroxide and organic peroxides using glutathione as a substrate, thereby preventing cellular damage caused by reactive oxygen species. GPx is a selenoenzyme, meaning it contains selenium in its active site, which is essential for its catalytic activity. The enzyme is widely distributed in various tissues, particularly in the liver and red blood cells, and is involved in various biological processes, including detoxification and regulation of cellular redox status. GPx activity can be influenced by factors such as selenium availability, oxidative stress levels, and the presence of other antioxidants. Dysregulation of GPx has been associated with various diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders. Overall, glutathione peroxidase is vital for maintaining cellular health and protecting against oxidative stress.

Glutathione peroxidase

9013-66-5: E.C. 1.11.1.9, Ec 1.11.1.9, GSH peroxidase, Glutathione peroxidase, Glutathione sulfhydryl peroxidase, Peroxidasa, Glutation, Peroxidase, Glutathion-, Peroxydase, Glutathion, Peroxynitrite reductase, Reduced glutathione peroxidase, Selenoglutathione peroxidase, Selenoperoxidase, Peroxidase, glutathione

Glutathione Peroxidase (GSH-Px; EC 1.11.1.9), a member of the peroxidase family, catalyzes the oxidation of reduced glutathione (GSH) to oxidized glutathione (

Glutathione Peroxidase

Glutathione peroxidase (EC 1.11.1.9) is an enzyme that reduces peroxides to limit oxidative damage, by catalyzing the following reaction:  2 GSH + H2O2 → GS-SG + 2 H2O  One unit of glutathione peroxidase will catalyze the conversion of 1.0 µmole of H2O2 per minute at pH 7.0 and 25 °C in the presence of reduced glutathione. Reduced glutahione is available here.

CAS 9013-66-5: Glutathione peroxidase

Glutathione peroxidase

Ref: IN-DA0039QF

Glutathione Peroxidase

Ref: TM-T80056

Glutathione peroxidase

Ref: 3D-FG166391