CAS: 903564-48-7

UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.

UM-164 is a molecule that was designed to inhibit the interaction between the drug and the receptor. The UM-164 binds to a region of tyrosine kinase that is important for cell proliferation and survival. This binding inhibits the ability of tyrosine kinase to bind to its receptors, which prevents cancer cells from growing and dividing. UM-164 has also been shown to have inhibitory properties against other molecules that are involved in cancer progression.

UM-164