CAS 90357-06-5: Bicalutamide
Formula:C18H14F4N2O4S
InChI:InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)
InChI key:InChIKey=LKJPYSCBVHEWIU-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C1=C(C#N)C=CC(NC(C(CS(=O)(=O)C2=CC=C(F)C=C2)(C)O)=O)=C1
Synonyms:- (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
- (±)-4′-Cyano-α,α,α-trifluoro-3-[(p-fluorophenyl)sulfonyl]-2-methyl-m-lactotoluidide
- 4-cyano-3-trifluoromethyl-N-(3-p-fluorophenylsulfonyl-2-hydroxy-2-methylpropionyl)aniline
- Bicalutamide (Subject to patent free)
- Casode
- Casodex
- Cosudex
- Ici 176334
- N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamid
- N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
- Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-
- See more synonyms
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Bicalutamide Crystalline Form II
CAS:Controlled ProductFormula:C18H14F4N2O4SColor and Shape:NeatMolecular weight:430.37Bicalutamide
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Formula:C18H14F4N2O4SColor and Shape:White Off-White PowderMolecular weight:430.06104Bicalutamide
CAS:BicalutamideFormula:C18H14F4N2O4SPurity:99.7%Color and Shape:WhiteMolecular weight:430.0610490357-06-5
CAS:Formula:C18H14F4N2O4SPurity:98%Color and Shape:SolidMolecular weight:430.3733727999999Bicalutamide
CAS:Androgen receptor antagonistFormula:C18H14F4N2O4SPurity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:430.37 g/molBicalutamide
CAS:Formula:C18H14F4N2O4SColor and Shape:White To Off-White SolidMolecular weight:430.37Bicalutamide
CAS:Formula:C18H14F4N2O4SPurity:≥ 98.0% (dried basis)Color and Shape:White or almost white powderMolecular weight:430.37Bicalutamide
CAS:Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting theFormula:C18H14F4N2O4SPurity:98% - 99.87%Color and Shape:Off-White Crystalline SolidMolecular weight:430.37Bicalutamide
CAS:Formula:C18H14F4N2O4SPurity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:430.37Bicalutamide
CAS:Controlled ProductApplications Non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal); Non-steroidal androgen receptor antagonist that binds the androgen receptor and prevents its activation. References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),Formula:C18H14F4N2O4SColor and Shape:WhiteMolecular weight:430.37
