2-Methyl-5-pyrrolidin-2-yl-pyridine, identified by its CAS number 90872-72-3, is a chemical compound characterized by a pyridine ring substituted with a pyrrolidine group and a methyl group. This compound features a five-membered nitrogen-containing heterocycle (pyrrolidine) attached to the pyridine, which is a six-membered aromatic ring. The presence of the methyl group at the second position of the pyridine enhances its lipophilicity, potentially influencing its biological activity and solubility properties. The compound may exhibit various pharmacological effects due to its structural features, making it of interest in medicinal chemistry. Its molecular structure suggests potential interactions with biological targets, which could be explored in drug development. Additionally, the compound's stability, reactivity, and potential applications in various fields, including pharmaceuticals and agrochemicals, can be influenced by its functional groups and overall molecular architecture. As with many nitrogen-containing heterocycles, it may also participate in hydrogen bonding and other intermolecular interactions, affecting its behavior in different environments.

2-methyl-5-pyrrolidin-2-yl-pyridine

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6-Methyl nornicotine is a pyridine derivative that is used in the manufacture of insecticides. This compound is a protonated form of nicotine and has been shown to have insecticidal effects. 6-Methyl nornicotine can be synthesized from nicotine by treatment with sodium borohydride in the presence of pyridine. The major products are 6-methyl-, 5,6-dimethyl-, and 5,6,7-trimethylnornicotine. 6-Methyl nornicotine is basic and has hydrogen bonding abilities. It also has a nitrogen atom that can bond to an oxygen atom in pyridine to form a six membered ring structure called a pyridinium ring.

6-Methyl nornicotine

6-Methyl Nornicotine

Applications Nicotine analog.
References Yamamoto, I., et al.: Agr. Biol. Chem., 27, 446 (1963)


CAS 90872-72-3: 2-methyl-5-pyrrolidin-2-yl-pyridine

6-Methyl nornicotine

Ref: 3D-FM25537

6-Methyl Nornicotine

Ref: IN-DA00GWR5

6-Methyl Nornicotine

Ref: TR-M325833

2-Methyl-5-(pyrrolidin-2-yl)pyridine

Ref: 10-F229093

2-Methyl-5-(pyrrolidin-2-yl)pyridine

Ref: 54-OR350511