Exenatide acetate is a synthetic peptide that mimics the action of the incretin hormone GLP-1 (glucagon-like peptide-1), which plays a crucial role in glucose metabolism. It is primarily used in the management of type 2 diabetes mellitus to improve glycemic control. The substance is characterized by its ability to stimulate insulin secretion in response to elevated blood glucose levels, inhibit glucagon release, and slow gastric emptying, thereby reducing postprandial blood sugar spikes. Exenatide acetate is administered via subcutaneous injection and has a prolonged action due to its acetate formulation, which enhances its stability and bioavailability. The peptide consists of 39 amino acids and has a molecular weight that reflects its peptide structure. Common side effects may include gastrointestinal issues such as nausea and vomiting, as well as potential risks of pancreatitis. Overall, Exenatide acetate represents a significant advancement in diabetes treatment, offering a mechanism that aligns with the body's natural regulatory processes for glucose homeostasis.

Exenatide acetate

914454-01-6: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-, acetate (1:?), Exenatide acetate, Exendin-4 acetate, Exendin 4 (Heloderma suspectum), acetate

Exendin-4 acetate is a 39 amino acid peptide.Exendin-4 acetate is a long-acting GLP-1 receptor agonist(IC50 = 3.22 nM).

Exendin-4 acetate

Exendin-4 acetate is a peptide hormone that belongs to the glucagon family. It is a potent stimulator of insulin release and has been used for the treatment of type 2 diabetes. Exendin-4 acetate is synthesized by recombinant DNA technology and can be quantified by HPLC. Exendin-4 acetate is a linear molecule with a linear range from 0.1 to 1000 pmol, making it suitable for quantitative measurements. The average response time for exendin-4 acetate is 9 minutes, which makes it ideal for use in experiments that require fast results. The detection wavelength for exendin-4 acetate is at 280 nm, which falls within the range of common UV detectors. A phosphate buffer solution or an acid solution can be used as the mobile phase in this experiment, with a flow rate of 1 ml/min.

CAS 914454-01-6: Exenatide acetate

Exendin-4 acetate

Ref: TM-T8748

Exendin-4 Acetate

Ref: 3D-PLB45401