CAS 915087-33-1: Enzalutamide
Formula:C21H16F4N4O2S
InChI:InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23,24)25)19(32)29(20)13-6-7-14(16(22)9-13)17(30)27-3/h4-9H,1-3H3,(H,27,30)
InChI key:InChIKey=WXCXUHSOUPDCQV-UHFFFAOYSA-N
SMILES:S=C1N(C(C)(C)C(=O)N1C2=CC(C(F)(F)F)=C(C#N)C=C2)C3=CC(F)=C(C(NC)=O)C=C3
Synonyms:- 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide
- Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methyl-
- Enzalutamide
- Mdv 3100
- Mdv3100
- S-Enzalutamide
- Xtandi
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Found 11 products.
Enzalutamide
CAS:Androgen receptor antagonistFormula:C21H16F4N4O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:464.4 g/mol4-(3-(1-(4--Cyano-3-(trifluoromethyl)phenyl)methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazolin-7-yl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile
CAS:Controlled ProductFormula:C30H18F6N6O2S2Color and Shape:NeatMolecular weight:672.623Enzalutamide
CAS:Formula:C21H16F4N4O2SColor and Shape:White To Off-White SolidMolecular weight:464.44Enzalutamide (MDV3100)
CAS:Formula:C21H16F4N4O2SPurity:98%Color and Shape:SolidMolecular weight:464.436Enzalutamide N-2'-(Trifluoromethyl)benzonitrile
CAS:Controlled ProductFormula:C28H16F7N5O2SColor and Shape:NeatMolecular weight:619.513Enzalutamide
CAS:Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).Formula:C21H16F4N4O2SPurity:100% - 99.7%Color and Shape:SolidMolecular weight:464.44Ref: TM-T6002
5mg48.00€10mg56.00€25mg74.00€50mg96.00€100mg154.00€200mg187.00€500mg274.00€1mL*10mM (DMSO)52.00€MDV 3100 (Enzalutamide)
CAS:Controlled ProductApplications MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer. References Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011);Formula:C21H16F4N4O2SColor and Shape:WhiteMolecular weight:464.44
