CAS 917377-74-3: Phosphine,1,1'-[(1R)-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diyl]bis[1,1-diphenyl-(9CI)

(R)-(-)-7,7Õ-Bis(Diphenylphosphino)-2,2Õ,3,3Õ-Tetrahydro-1,1Õ-Spirobiindane

(R)-SDP is an organophosphorus compound that is used as a ligand. It has been shown to catalyze the hydroamination of amines with alkyl halides and benzene, giving products with high enantioselectivity. The hydrogenated form of (R)-SDP has been prepared by reaction with lithium diisopropylamide at -78 ˚C. The synthesis of the hydrogenated form was accomplished in three steps: (1) reaction of sodium hydride with (2) 2-bromoethanol and (3) N-bromosuccinimide, followed by reaction with lithium diisopropylamide at -78 ˚C. This compound can be used for preparative purposes, such as in the production of rhodium complexes or anti-cancer drugs.

(R)-(+)-7,7'-Bis(diphenylphosphino)-2,2',3,3'-tetrahydro-1,1'-spirobiindane, min. 97% (R)-SDP