CAS 918-01-4: Bromodichloronitromethane

Bromodichloronitromethane (BDN) is a chemical that has high cytotoxicity. It is used in analytical chemistry for the determination of hydrated and other inorganic acids. It is also used as an insecticide and agricultural herbicide. BDN has been shown to be harmful to mammalian cells, causing health effects such as death, necrosis, and chromosomal aberrations. BDN has been shown to react with glutathione transferase enzymes found in ovaries and other tissues, leading to a reaction rate that can be measured by spectroscopy at 275 nm. The synthesis of BDN involves reacting trichloronitromethane with bromine and sodium nitrite at 300°C.

Applications Halonitromethanes (HNMs) are a recently identified class of disinfection byproducts (DPBs) in drinking water that are mutagenic in Salmonella and potent inducers of DNA strand breaks in mammalian cells. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Koch, W., et al.: Carcinogenesis, 15, 79 (1994), Giller, S., et al.: Mutat. Res., 348, 147 (1995), Pegram, R., et al.: Toxicol. Appl. Pharmacol., 144, 183 (1997),

Bromodichloronitromethane is a Halonitromethane compound, classified as a disinfection by-product (DBP) present in drinking water.