CAS 920113-03-7: P 276-00
Formula:C21H20ClNO5·ClH
InChI:InChI=1S/C21H20ClNO5.ClH/c1-23-7-6-12(14(23)10-24)19-15(25)8-16(26)20-17(27)9-18(28-21(19)20)11-4-2-3-5-13(11)22;/h2-5,8-9,12,14,24-26H,6-7,10H2,1H3;1H/t12-,14+;/m1./s1
InChI key:InChIKey=OOVTUOCTLAERQD-OJMBIDBESA-N
SMILES:OC=1C(=C2C(C(=O)C=C(O2)C3=C(Cl)C=CC=C3)=C(O)C1)[C@H]4[C@H](CO)N(C)CC4.Cl
Synonyms:- 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methyl-3-pyrrolidinyl]-, hydrochloride (1:1)
- P 276-00
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Found 5 products.
Riviciclib hydrochloride
CAS:Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.Formula:C21H20ClNO5·HClPurity:99.36%Color and Shape:SolidMolecular weight:438.3P276-00
CAS:P276-00 is an inhibitor of the MCL-1 protein, which is a pro-apoptotic protein. It has been shown to inhibit polymerase chain reaction (PCR) amplification of DNA in hl-60 cells and miapaca-2 cells. P276-00 is also active against cancer cells that have acquired drug resistance through the activation of MCL-1. This inhibitor blocks the kinase activity associated with MCL-1 and has been shown to be effective in treating bowel diseases, urinary infections, and cancer.Formula:C21H21Cl2NO5Purity:Min. 95%Molecular weight:438.3 g/mol
