CAS: 923981-14-0

Centanafadine HCl is a NE/DA reuptake inhibitor, also affects serotonin (IC50: NE 6 nM, DA 38 nM, serotonin 83 nM).

Centanafadine hydrochloride

Applications Centanafadine Hydrochloride is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) used as a treatment for attention deficit hyperactivity disorder (ADHD) that is in phase II clinical trials.

Centanafadine-d7 Hydrochloride is a research chemical that has various applications in the field of catalysis and bioavailability studies. It is used as an electrode material due to its high conductivity and stability. The presence of zirconium oxide and aluminum enhances its catalytic properties, making it suitable for reactions involving fatty acids and other organic compounds. Centanafadine-d7 Hydrochloride is also used in the purification process to remove contaminants, such as metallic impurities and electrolytes, from solutions. Its high blood calcium affinity makes it useful in medical research related to calcium homeostasis. Additionally, this compound can be employed in plasmid isolation procedures due to its ability to bind DNA fragments through isothiocyanate chemistry. Rhodium catalysts are commonly used with Centanafadine-d7 Hydrochloride for efficient synthesis reactions.