CAS 93100-99-3: 4-Chloro-N-[(2Z)-1-(2-phenylethyl)-2-piperidinylidene]benzenesulfonamide

W-15-d4 is a benzodiazepine receptor ligand that is an analog of zolpidem. It has been shown to bind to the benzodiazepine receptor with micrometer affinity. Binding of this drug to the benzodiazepine receptor leads to increased thermal expansion and tail-flick latency in mice. W-15-d4 is effective against aviadenovirus, which causes a respiratory disease in chickens, by inhibiting RNA synthesis. This drug has also been shown to inhibit the replication of human influenza A virus (H1N1) and H5N1 avian influenza virus in vitro. W-15-d4 binds to the same site on the RNA polymerase as zolpidem.

Applications W-15 is an analog of the µ-opioid receptor agonist fentanyl. It has been shown to be a potent analgesic in the mouse phenylquinone writhing assay. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Knaus, E., et al.: U.S., US 4468403 A 19840828. (1984)