
CAS 93718-83-3: 2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione
Formula:C14H14O4S2
InChI:InChI=1S/C14H14O4S2/c15-5-7-19-13-11(17)9-3-1-2-4-10(9)12(18)14(13)20-8-6-16/h1-4,15-16H,5-8H2
InChI key:InChIKey=MAASHDQFQDDECQ-UHFFFAOYSA-N
SMILES:O=C1C=2C(C(=O)C(SCCO)=C1SCCO)=CC=CC2
Synonyms:- 1,4-Naphthalenedione, 2,3-bis[(2-hydroxyethyl)thio]-
- 1,4-Naphthoquinone, 2,3-bis[(2-hydroxyethyl)thio]-
- 2,3-Bis(2-hydroxyethylsulfanyl)naphthalene-1,4-dione
- 2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione
- 2,3-Bis[(2-hydroxyethyl)sulfanyl]-1,4-naphthoquinone
- 2,3-Bis[(2-hydroxyethyl)thio]-1,4-naphthalenedione
- NSC 95397
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Found 5 products.
2,3-Bis(2-Hydroxyethylthio)-1,4-Naphthalenedione
CAS:2,3-Bis(2-Hydroxyethylthio)-1,4-NaphthalenedionePurity:98%Molecular weight:310.39g/molNSC 95397
CAS:NSC 95397 is a chemical inhibitor of the enzyme protein kinase C (PKC). It binds to PKC and prevents it from catalyzing phosphorylation of proteins. This inhibition has been shown to be effective in the treatment of blood disorders, such as leukemia. NSC 95397 also inhibits apoptosis, or programmed cell death, by preventing the activation of enzymes that regulate mitochondrial membrane potential, thereby blocking the release of cytochrome c and other factors that initiate apoptosis. The inhibitory properties of this drug have also been shown to potentiate the effects of other agents that induce cell death, such as tumor necrosis factor-α. This agent has also been shown to suppress antibody production in mice.Formula:C14H14O4S2Purity:Min. 95%Molecular weight:310.39 g/mol2,3-bis(2-hydroxyethylsulfanyl)naphthalene-1,4-dione
CAS:Formula:C14H14O4S2Purity:97%Color and Shape:SolidMolecular weight:310.3886NSC 95397
CAS:NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).Formula:C14H14O4S2Purity:97.12%Color and Shape:SolidMolecular weight:310.39