![Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3′,5′-(hydrogen phosphate), sodium salt (1:1)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F294753-adenosine-8-4-chlorophenyl-thio-cyclic-35-hydrogen-phosphate-sodium-salt-1-1.webp&w=3840&q=75)
CAS 93882-12-3: Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3′,5′-(hydrogen phosphate), sodium salt (1:1)
Formula:C16H15ClN5O6PS·Na
InChI:InChI=1S/C16H15ClN5O6PS.Na/c17-7-1-3-8(4-2-7)30-16-21-10-13(18)19-6-20-14(10)22(16)15-11(23)12-9(27-15)5-26-29(24,25)28-12;/h1-4,6,9,11-12,15,23H,5H2,(H,24,25)(H2,18,19,20);/t9-,11-,12-,15-;/m1./s1
InChI key:InChIKey=PHGQLNFIDGOCGJ-DNBRLMRSSA-N
SMILES:S(C=1N(C=2C(N1)=C(N)N=CN2)[C@@H]3O[C@]4([C@]([C@H]3O)(OP(=O)(O)OC4)[H])[H])C5=CC=C(Cl)C=C5.[Na]
Synonyms:- 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv.
- 8-(p-Chlorophenylthio)-cAMP sodium salt
- Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3′,5′-(hydrogen phosphate), monosodium salt
- Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3′,5′-(hydrogen phosphate), sodium salt (1:1)
- sodium (4aR,6R,7R,7aS)-6-{6-amino-8-[(4-chlorophenyl)sulfanyl]-9H-purin-9-yl}-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide
- Adenosine, 8-((4-chlorophenyl)thio)-, cyclic 3',5'-(hydrogen phosphate), monosodium salt
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Found 5 products.
8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt
CAS:8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt (8-CPT-cAMP) is a cytosolic second messenger that regulates physiological processes. It interacts with the G protein coupled receptor 2-adrenergic receptor, and activates adenylyl cyclase to produce cAMP. 8-CPT-cAMP also induces mitochondrial membrane potential depolarization and Ca2+ release from the endoplasmic reticulum, which leads to cell death. The pro-apoptotic protein Bax is upregulated by 8-CPT-cAMP in cells and contributes to cell death.Formula:C16H14ClN5NaO6PSPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:493.79 g/mol8-(4-Chlorophenylthio)adenosine-3'',5''-cyclic monophosphate
CAS:Formula:C16H14ClN5NaO6PSMolecular weight:493.798-CPT-cAMP
CAS:Formula:C16H14ClN5NaO6PSPurity:99%Color and Shape:SolidMolecular weight:493.793791000000068-CPT-cAMP sodium salt
CAS:Controlled ProductApplications 8-CPT-cAMP is an efficient activator of cGK and cAMP-PK, and inhibitor of PDE.Formula:C16H15ClN5O6PS•NaColor and Shape:NeatMolecular weight:471.8122998-CPT-Cyclic AMP (sodium salt)
CAS:8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA) and a potent inhibitor of cyclic GMP-specific phosphodiesterase (PDE VA) with an inhibitory concentration (IC50) of 0.9 μM. It also inhibits PDE III and PDE IV while significantly activating Epac, demonstrating diverse pharmacological activities [1] [2].Formula:C16H14ClN5NaO6PSColor and Shape:White PowderMolecular weight:493.79
