The chemical substance with the name "{4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]bicyclo[2.2.2]oct-1-yl}acetic acid" and CAS number "942999-61-3" is characterized by its complex molecular structure, which includes a bicyclic octane framework and a pyrimidine-oxazine moiety. This compound features an amino group, which may contribute to its potential biological activity, possibly influencing interactions with biological targets. The presence of the acetic acid functional group suggests that it may exhibit acidic properties, which could affect its solubility and reactivity in various environments. The intricate arrangement of functional groups and rings indicates that this substance may have specific pharmacological properties, making it of interest in medicinal chemistry. Its unique structure may also lead to distinctive physical and chemical properties, such as stability, melting point, and solubility, which are essential for its application in research or therapeutic contexts. Further studies would be necessary to fully elucidate its characteristics and potential uses.

{4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]bicyclo[2.2.2]oct-1-yl}acetic acid

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DGAT-1 inhibitor 2: effective against obesity, targets enzyme in triglyceride synthesis for diabetes treatment.

DGAT-1 inhibitor 2

DGAT-1 inhibitor 2 is an oxadiazole derivative that has been shown to be a potent inhibitor of the DGAT-1 enzyme in humans. This compound has been shown to have a permeability profile in animals that is similar to meglumine, a known DGAT-1 inhibitor. The compound also binds to elements on the surface of cells that are thought to be important for the catalytic activity of DGAT-1 enzymes, and has demonstrated attenuation of obesity and metabolic syndrome in animal models.

DGAT-1 inhibitor 2 is most likely active against obesity by inhibiting the synthesis of triglycerides from glucose in adipose tissue. DGAT-1 inhibitors are also thought to have potential therapeutic applications for diabetes mellitus type II and other conditions associated with insulin resistance.

CAS 942999-61-3: {4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]bicyclo[2.2.2]oct-1-yl}acetic acid

DGAT-1 inhibitor 2

Ref: TM-T11016

DGAT-1 inhibitor 2

Ref: 54-BUP12041

DGAT-1 inhibitor 2

Ref: 3D-SMB99961