CAS 943-03-3: 2-Benzothiazolecarbonitrile, 6-methoxy-

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2-Cyano-6-methoxy benzothiazole is a bioluminescent molecule that emits light when reacted with an enzyme from the firefly luciferase family. This molecule has been used in assays for detecting gram-negative bacteria and in vitro assays for measuring the enzyme activities of cytochrome P450, β-lactamases, and DNA gyrase. 2-Cyano-6-methoxy benzothiazole has also been used to measure human serum concentrations of drugs such as acetaminophen and phenytoin. The luminescence intensity is proportional to the concentration of these drugs in the serum. 2-Cyano-6-methoxy benzothiazole is synthesized by reacting a hydroxyl group with an inorganic acid.

6-Methoxy-1,3-benzothiazole-2-carbonitrile