CAS 944396-07-0: Buparlisib
Formula:C18H21F3N6O2
InChI:InChI=1S/C18H21F3N6O2/c19-18(20,21)13-9-15(22)23-11-12(13)14-10-16(26-1-5-28-6-2-26)25-17(24-14)27-3-7-29-8-4-27/h9-11H,1-8H2,(H2,22,23)
InChI key:InChIKey=CWHUFRVAEUJCEF-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C=1C(C=2C=C(N=C(N2)N3CCOCC3)N4CCOCC4)=CN=C(N)C1
Synonyms:- 2-Pyridinamine, 5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-
- 5-(2,6-Dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridine-2-amine
- Bkm 120
- Bkm 120Nx
- Bkm120
- Buparlisib
- Nvp-Bkm 120
- Nvp-Bkm120
- 5-(2,6-diMorpholinopyriMidin-4-yl)-4-(trifluoroMethyl)pyridin-2-aMine
- 5-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine
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Found 7 products.
NVP-BKM 120-d16 Hydrochloride
CAS:Controlled ProductFormula:C18H6D16ClF3N6O2Color and Shape:NeatMolecular weight:462.955-(2,6-Di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine
CAS:Formula:C18H21F3N6O2Purity:98%Color and Shape:SolidMolecular weight:410.3935Buparlisib
CAS:Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).Formula:C18H21F3N6O2Purity:95.32% - 98.45%Color and Shape:SolidMolecular weight:410.39Ref: TM-T1827
5mg63.00€10mg85.00€25mg94.00€50mg115.00€100mg144.00€200mg235.00€500mg424.00€1mL*10mM (DMSO)69.00€BKM 120
CAS:Inhibitor of pan-class I PI3K family of lipid kinases; antineoplasticFormula:C18H21O2N6F3Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:410.39 g/molNVP-BKM 120-13C3 Hydrochloride
CAS:Controlled ProductFormula:C15C3H22ClF3N6O2Color and Shape:NeatMolecular weight:449.83NVP-BKM 120
CAS:Controlled ProductStability Hygroscopic Applications NVP-BKM 120 is a novel anti-tumor active compound that is selective in that it inhibits specifically PI3 kinase activating cell death in glioma cells. Glioma cells being those that proliferate from tumors in the brain or the spine. References Koul, D. et al.: Clin. Cancer Res., 18, 184 (2012);Formula:C18H21F3N6O2Color and Shape:White To Off-WhiteMolecular weight:410.39
