CAS 94470-67-4: Cromakalim
Formula:C16H18N2O3
InChI:InChI=1/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3/t14-,15+/s2
InChI key:InChIKey=TVZCRIROJQEVOT-PVRQQBJHNA-N
SMILES:O[C@@H]1[C@H](C=2C(OC1(C)C)=CC=C(C#N)C2)N3C(=O)CCC3
Synonyms:- (+-)-trans-3-Hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-6-chromancarbonitrile
- (3R,4S)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydro-2H-chromene-6-carbonitrile
- (3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydro-2H-chromene-6-carbonitrile
- 2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, (3R,4S)-rel-
- 2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, trans-(+-)-
- 3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydro-2H-chromene-6-carbonitrile
- Brl 34915
- Cromakalim [INN:BAN]
- Cromakalime
- Cromakalime [French]
- Cromakalimum
- See more synonyms
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Found 4 products.
Cromakalim
CAS:Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.Formula:C16H18N2O3Purity:99.39%Color and Shape:SolidMolecular weight:286.33(+/-)-Cromakalim
CAS:Cromakalim is a potassium channel opener that is used to treat cardiac arrhythmia. It blocks the voltage-gated potassium channels in the heart and relieves symptoms of atrial fibrillation, including papillary muscle spasm and tachycardia. Cromakalim also has been shown to have effects on the central nervous system, where it blocks neuronal death and inhibits brain functions. This drug has bronchoconstrictor properties and can cause cell lysis in some cells. Cromakalim is an inhibitor of phospholipase A2 (PLA2) and cyclooxygenase (COX), which are enzymes that produce inflammatory mediators.Formula:C16H18N2O3Purity:Min. 95%Molecular weight:286.33 g/molRef: 3D-FC20586
Discontinued product(+/-)-Cromakalim
CAS:Controlled ProductApplications Causes vasodilation by activation of potassim channels. References Lijnen, P., et al.: Eur. J. Clin. Pharmacol., 37, 609(1989), Spinelli, W., et al.: Eur. J. Pharmacol., 179, 243 (1990)Formula:C16H18N2O3Color and Shape:NeatMolecular weight:286.33
