![2,4-Dichloro-N-(1-methylethyl)-N-[2-[(1-methylethyl)amino]ethyl]benzenesulfonamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F102463-24-dichloro-n-1-methylethyl-n-2-1-methylethyl-amino-ethyl-benzenesulfonamide.webp&w=3840&q=75)
CAS 946387-07-1: 2,4-Dichloro-N-(1-methylethyl)-N-[2-[(1-methylethyl)amino]ethyl]benzenesulfonamide
Formula:C14H22Cl2N2O2S
InChI:InChI=1S/C14H22Cl2N2O2S/c1-10(2)17-7-8-18(11(3)4)21(19,20)14-6-5-12(15)9-13(14)16/h5-6,9-11,17H,7-8H2,1-4H3
InChI key:InChIKey=IHYZMEAZAIFMTN-UHFFFAOYSA-N
SMILES:S(N(CCNC(C)C)C(C)C)(=O)(=O)C1=C(Cl)C=C(Cl)C=C1
Synonyms:- 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
- 2,4-Dichloro-N-propan-2-yl-N-[2-(propan-2-ylamino)ethyl]benzenesulfonamide
- 946387-07-1
- Ab 159908
- Benzenesulfonamide, 2,4-dichloro-N-(1-methylethyl)-N-[2-[(1-methylethyl)amino]ethyl]-
- Gr Cg Dswny1& 1& 2My1& 1
- Rn 1734
- 2,4-Dichloro-N-(1-methylethyl)-N-[2-[(1-methylethyl)amino]ethyl]benzenesulfonamide
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Found 7 products.
((2,4-dichlorophenyl)sulfonyl)(isopropyl)(2-((isopropyl)amino)ethyl)amine
CAS:2,4-Dichlorophenylsulfonyl isopropyl (2-((isopropyl)amino)ethyl)amine ((2,4-DAPIS)) is a potent and selective inhibitor of the protein kinase PKCζ. It has been shown to be active in animal models of chronic cough and bronchial asthma. The 2,4-DAPIS binds to the ATP site on PKCζ and inhibits its activity by binding to the catalytic domain of the enzyme. Inhibition of PKCζ leads to decreased angiotensin system activity, which in turn decreases chronic cough and bronchial asthma. The 2,4-DAPIS also blocks potassium channels TRPV4, which may lead to an improvement of disease activity.Formula:C14H22Cl2N2O2SPurity:Min. 95%Molecular weight:353.31 g/mol2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
CAS:Formula:C14H22Cl2N2O2SPurity:98%Color and Shape:SolidMolecular weight:353.3077RN-1734
CAS:RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)Formula:C14H22Cl2N2O2SPurity:99.1% - 99.30%Color and Shape:SolidMolecular weight:353.31
