CAS 947-92-2: N-Nitrosodicyclohexylamine

N-Nitrosodicyclohexylamine (NDCHA), an N-nitrosocompound, exhibits anti-androgenic activity by competitively binding to the androgen receptor (AR) in opposition

N-Nitrosodicyclohexylamine (NDCA) is a chemical that is used as a corrosion inhibitor. The stability of NDCA in the environment has been studied extensively and found to be resistant to many conditions including heat, light, and pH. NDCA is absorbed by the skin or ingested and has been shown to cause genotoxic effects in human lymphocytes. The genotoxic potential of NDCA has also been demonstrated in V79 cells. NDCA reacts with amines to form an intermediate that spontaneously decomposes into nitrosamines, which are carcinogenic. This reaction mechanism was confirmed using analytical methods such as gas chromatography-mass spectrometry (GC-MS).

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