CAS 948-71-0: 5-Hydroxythiabendazole

5-Hydroxythiabendazole is a reactive benzimidazole compound. It is used as a reagent in analytical methods to detect the presence of 5-hydroxythiabendazole and fenbendazole sulfone in human serum and other biological samples. 5-Hydroxythiabendazole can be used to measure enzyme activity by adding it to a substrate, and measuring the light emitted by the substrate's reaction with the drug. It has been shown that 5-hydroxythiabendazole can inhibit tubule cell growth in a rat model of chronic renal failure and may have anthelmintic properties. The effectiveness of this drug has been studied using monoclonal antibodies against 5-hydroxythiabendazole, which are fluorescently labeled with fluorescein isothiocyanate (FITC) or phycoerythrin (PE). The use of these antibodies

5-OH TBZ, a thiabendazole metabolite, lacks anthelmintic effect on A. caninum larvae growth.

Applications 5-Hydroxy Thiabendazole is the major metabolite of Thiabendazole (T344150). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Fujitani, T., et al.: Food Chem. Toxicol., 29, 265 (1991), Mizutani, T., et al.: Chem. Res. Toxicol., 6, 174 (1993), Dalvie, D., et al.: J. Agric. Food Chem., 42, 2964 (2006),