CAS: 956483-03-7

FV-100 (Valnivudine HCl), API for CF-1743, is a potent, oral anti-vaxx-zoster drug with low in vivo toxicity.

Applications FV 100-d7 is labelled FV 100 (F870000), an orally available nucleoside analogue prodrug of CF-1743 (C291710) which is used for the treatment of herpes zoster, or shingles, which is an infection caused by the reactivation of varicella zoster virus or VZV. References McGuigan, C., et al.: J. Med. Chem., 43, 4993 (2000); McGuigan, C., et al.: J. Antimicro. Chemother., 60, 1316 (2007); Andrei, G., et al.: Antimicro. Agents Chemother., 49, 1081 (2005)

FV-100

Valnivudine hydrochloride is an antiviral drug that inhibits the replication of herpes viruses by inhibiting viral DNA polymerase. It is used to treat shingles and post-herpetic neuralgia. Valnivudine hydrochloride has been shown to be effective in reducing the severity and duration of symptoms, as well as reducing significant morbidity, when given to patients with shingles or post-herpetic neuralgia. Valnivudine hydrochloride also has a role in the prevention of transmission of HIV from mother to child during pregnancy, childbirth, and breastfeeding.