![N,N-Diethyl-2-[4-(2-fluoroethoxy)phenyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-acetamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F490994-n-n-diethyl-2-4-2-fluoroethoxy-phenyl-57-dimethylpyrazolo-15-a-pyrimidine-3-acetamide.webp&w=3840&q=75)
CAS 958233-07-3: N,N-Diethyl-2-[4-(2-fluoroethoxy)phenyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-acetamide
Formula:C22H27FN4O2
InChI:InChI=1S/C22H27FN4O2/c1-5-26(6-2)20(28)14-19-21(17-7-9-18(10-8-17)29-12-11-23)25-27-16(4)13-15(3)24-22(19)27/h7-10,13H,5-6,11-12,14H2,1-4H3
InChI key:InChIKey=FLZZFWBNYJNHMY-UHFFFAOYSA-N
SMILES:C(C(N(CC)CC)=O)C1=C2N(N=C1C3=CC=C(OCCF)C=C3)C(C)=CC(C)=N2
Synonyms:- Pyrazolo[1,5-a]pyrimidine-3-acetamide, N,N-diethyl-2-[4-(2-fluoroethoxy)phenyl]-5,7-dimethyl-
- 2-[2-[4-(2-Fluoroethoxy)phenyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl]-N,N-diethylacetamide
- N,N-Diethyl-2-[4-(2-fluoroethoxy)phenyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-acetamide
- DPA 714
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Found 3 products.
DPA-714
CAS:DPA-714 is a nucleophilic agent which is metabolized by cytochrome P450 (CYP) 3A4 to its active form, fluoroacetic acid. This drug has immunomodulatory effects, and it has been shown to reduce the uptake of fluoroacetic acid by microglia cells. DPA-714 also inhibits the production of inflammatory cytokines such as IL-6 in human macrophages. DPA-714 has been shown to be effective against bowel disease in rats, and it may have therapeutic potential for treatment of inflammatory bowel disease in humans. DPA-714 binds to the activated receptor on microglia cells, leading to activation and proliferation of these cells. It also binds to the occipital cortex with high affinity, suggesting that this drug may have potential for treating brain disorders such as Alzheimer’s Disease.Formula:C22H27FN4O2Purity:Min. 95%Molecular weight:398.5 g/molDPA-714
CAS:DPA-714: a TSPO ligand (Ki=7 nM) with a fluorine atom for PET imaging of inflammation and brain tumors.Formula:C22H27FN4O2Purity:99.52%Color and Shape:SolidMolecular weight:398.47Ref: TM-T15162
1mg86.00€5mg180.00€10mg269.00€25mg499.00€50mg723.00€100mg1,026.00€200mg1,415.00€1mL*10mM (DMSO)188.00€
