Azetidin-3-ylmethanol is a chemical compound characterized by its azetidine ring structure, which is a four-membered saturated heterocycle containing one nitrogen atom. The compound features a hydroxymethyl group (-CH2OH) attached to the third carbon of the azetidine ring, contributing to its reactivity and potential applications in organic synthesis. Azetidin-3-ylmethanol is typically a colorless to pale yellow liquid or solid, depending on its purity and specific conditions. It is soluble in polar solvents, such as water and alcohols, due to the presence of the hydroxymethyl group, which can engage in hydrogen bonding. The compound may exhibit biological activity, making it of interest in medicinal chemistry and drug development. Its unique structure allows for various chemical modifications, which can lead to the synthesis of derivatives with enhanced properties. As with many nitrogen-containing heterocycles, azetidin-3-ylmethanol may participate in nucleophilic reactions, making it a valuable intermediate in the synthesis of more complex organic molecules.

azetidin-3-ylmethanol

3-(Hydroxymethyl)azetidine

3-(Hydroxymethyl)azetidine is a chemical compound that has a high affinity for the 5-HT1A receptor. It is a lead compound for the development of drugs to treat depression, anxiety and other mood disorders. 3-(Hydroxymethyl)azetidine inhibits the reuptake of serotonin by blocking the transporter responsible for its reuptake. This drug also has an inhibitory effect on 5-HT1A receptors in vitro and in vivo. 3-(Hydroxymethyl)azetidine binds to the 5-HT1A receptor with high affinity and acts as an antagonist, preventing agonists from binding to it. Nucleophilic substitution reactions can be used to synthesize this molecule as well as nucleophilic addition reactions with formaldehyde or methyl iodide.

CAS 95849-02-8: azetidin-3-ylmethanol

3-(Hydroxymethyl)azetidine

Ref: 54-OR308022

3-(Hydroxymethyl)azetidine

Ref: 3D-VDA84902

Azetidin-3-ylmethanol

Ref: IN-DA00H7AY